ERF and Alzheimer disease: The known gene ereb100 (AC209257.4_FG006) around the locus S6_153235783 related to AD (Figure 3B; Supplementary Table 3) belongs to the APETALA2/Ethylene-responsive factor (AP2/ERF), which plays an active role in growth, development, and adaptation to abiotic stresses in maize (Zhang et al., 2022).