PLOD1 and COVID-19: Besides, the decreased level of testosterone with respect to LH, the decreased number or concentration of sperm cells, the decreased volume of semen, the increased fragmented DNA in the sperm cells, and the deregulated sex function in patients with COVID-19 probably represent fundamental damages in the reproductive system resulting from the impacts of SARS-2 on the controlling region of endocrine and sperm production systems in the central nervous system.