The fifth study reported GH levels in a combined group of individuals with TS and complete gonadal dysgenesis with 46XX karyotype, noting that those with DM had higher levels of plasma GH at the 15 and 30 minute time points; however, the frequency of abnormal GH responses in the diabetic group was not higher than in the non-diabetic group (33). Here, GH1 is linked to gonadal dysgenesis.