In Model II (adjusting for gender, ethanol consumption, habit of exercise, smoking status, age, DBP, SBP, AST, GGT, ALT, TC, FPG, and HbA1c), the risk of DM increased by 65% for each unit increase in CMI (HR: 1.65, 95%CI: 1.43-1.90, P<0.0001). The gene discussed is GPT; the disease is diabetes mellitus.