As univariate logistic regression analysis showed (Table 4), age, duration of diabetes, history of hypertension, SBP, DBP, ALT, urea, Cr, eGFR, HDL-C, CRP, RC, NLR, MLR, and PHR were independently associated with PAD occurrence in T2DM patients (P < 0.05). This evidence concerns the gene CRP and hypertensive disorder.