CXCR4 and neoplasm: The percentages of CD8+ TALs in untreated TgMISIIR-TAg-Low mice were lower than those in tumor-bearing WT mice (Figure 3D, p = 0.03), but their numbers increased after OV-CXCR4-A treatment compared with untreated and OV-EGFP-treated tumors (Figure 3D; p = 0.005 and p = 0.04).