BMPR2 and pulmonary arterial hypertension: Pathogenic BMPR2 mutations result in BMPR2haploinsufficiency with a decrease in pulmonary vascular BMPR2 proteinexpression; notably, BMPR2 expression is also decreased in the pulmonaryvasculature of patients with other forms of pulmonary hypertension, suggestingmechanistic parallels between the various subgroups [34].