On the other hand, changes in energy metabolism were also observed in hepatocytes (Figure 2(b)), in which activation of PPARγ and PPARβ/δ promotes glycolysis but decreases activation of TAC, thereby increasing the presence of precursors in the metabolism of glycerol, favoring the synthesis of triglycerides, promoting the accumulation of lipids and the development of nonalcoholic fatty liver, and altering systemic energy function. Here, PPARG is linked to non-alcoholic fatty liver.