Another study of untreated women with HBV infection during pregnancy and postpartum, which excluded women who started antiviral therapy during pregnancy for postnatal analysis, found a sudden increase in ALT and HBV DNA during the third trimester and early postpartum period in women with CHB; however, baseline ALT, HBV DNA, HBeAg-positive status, gestational age, and delivery times were not predictors of undesirable clinical outcomes, including spontaneous abortion, hepatic flare, premature delivery, GDM, pre-eclampsia, and liver failure (32). The gene discussed is GPT; the disease is liver failure.