TNFRSF1B and rheumatoid arthritis: The TBPII was translated into Etanercept/Enbrel®, a fusion protein with the Fc portion of immunoglobulin, for the treatment of mainly Rheumatoid Arthritis but also other autoimmune and inflammatory pathologies such as Psoriatic arthritis, Juvenile idiopathic arthritis and Ankylosing spondylitis.