A similar study found knockout of DCs reduced the clearance of activated HSCs and delayed the fibrotic reversal process during the reversal phase of CCL4-induced hepatic fibrosis in mice (34).However, it also reported that although DCs can promote the activation of HSCs, the depletion of DCs does not affect the evolution of liver fibrosis in CCL4-induced hepatic fibrosis (35). Here, CCL4 is linked to Hepatic fibrosis.