Briefly, the renal DACH1 and TCF21 expression was positively correlated with eGFR in CKD patients (DACH1, P = 7.15e-5, R2 = 0.554; TCF21, P = 5.34e-5, R2 = 0.566), whereas it was negatively correlated with SCr levels (DACH1, P = 0.0022, R2 = 0.366; TCF21, P = 5.04e-7, R2 = 0.707). Here, DACH1 is linked to chronic kidney disease.