In Figure 5B and Table S10, hypermethylation of STGs was shown to play an important role in several tumors, as TMPRSS2 in UVM and GBM; ACE2 in LIHC and ESCA; AXL in MESO, LIHC and PAAD; NRP1 in MESO, LIHC, ACC, LGG and HNSC; and SCARB1 in PRAD, THYM, SKCM, UVM were considered as protective factors for good survival (HR<1), while TMPRSS2 in LUAD, KIRP and KIRC; ACE2 in ACC and UVM; AXL in ACC; NRP1 in KIRC; and SCARB1 in LGG and KIRC were regarded as risk factors for poor survival (HR>1). The gene discussed is ACE2; the disease is glioblastoma.