Previous researchers have found that in patients with NSCLC, the higher the methylation level of EPHB6, HS3ST2, DAL-1, and TMEM88 genes, the greater the risk of metastasis, while the lower methylation of the ELMO3 gene, the greater the risk of NSCLC metastasis. Here, ELMO3 is linked to non-small cell lung carcinoma.