TRPA1 and osteoarthritis: Meanwhile, TRPA1 has been reported to be related to neurogenic inflammation, osteoarthritis, allergic dermatitis, asthma, inflammatory bowel disease, migraine, cancer pain, gout, and other diseases, and it is a promising drug therapy target (Moilanen et al., 2012; Lucaciu and Connell, 2013; Nassini et al., 2014; Zygmunt and Högestätt, 2014; Abdel-Magid, 2021).