PWRN1 and cancer: It is worth mentioning that the four verified lncRNAs as a miRNA sponge are widely reported in cancers, such as the GATA3-AS1/miR-495-3p/CENPU axis in breast cancer (Lin et al., 2021), and the PWRN1/miR-214-5p axis in osteosarcoma (Shi et al., 2020).