Studies suggest a potential link between this periodontal disease and PCOS through activation of different proinflammatory incidents like activation of different reactive oxygen species, myeloperoxidase, oxidative stress, inflammatory cytokines (such as IL-6 and TNF-α), high-sensitivity C-reactive protein (hs-CRP), adhesion molecules, and blood lymphocytes and monocytes [8-11]. The gene discussed is MPO; the disease is polycystic ovary syndrome.