They have a very important role in migrating lymphoid and myeloid cells' physiological rearrangement of tissues, including organogenesis, normal growth, embryonic growth, angiogenesis, and ovulation [14]. This study aims to evaluate the possible linkage between different indices of gingival health, including the salivary MMP-9, to the polycystic ovary status in women with PCOS from Babol Northern Iran. This evidence concerns the gene MMP9 and polycystic ovary syndrome.