At a cutoff of NGAL value of 150 ng/ml, sensitivity and specificity for AKI diagnosis keeping pRIFLE at 12 hours as the gold standard was 85.3% (68.9-95), 88.2% (72.5-96.7) and 76.5% (62.1-91.3) at 0, 12 and 48 hours (Table 2). This evidence concerns the gene LCN2 and acute kidney injury.