KLF2 and gastric cancer: Although this study provides a rationale for the role of KLF2 in GC pathogenesis, we did not further investigate the effect of epigenetic alterations on KLF2 underexpression in GC nor did we assess the number of patients who developed KLF2 underexpression in GC, and therefore, we will continue in-depth studies through databases and clinical trials in the future.