Remarkably similar results were mentioned by Geetha et al. [85], Huang et al. [86], and Xianchu et al. [76], who found that rutin suppressed oxidative stress via lowering production of ROS and MDA and by augmenting antioxidant status through increasing SOD, GSH, and GPx in several models of cardiovascular disease. This evidence concerns the gene SOD1 and cardiovascular disorder.