ANGPT1 and septic shock: The results showed that the Ang-1/2 ratios were significantly lower in patients with septic shock (Ang-1/2 ratios = 0.14) compared with severe sepsis patients (Ang-1/2 ratios = 0.53) and control individuals (Ang-1/2 ratios = 0.8) (p = 0.001 and <0.0001, respectively) (Table 1 & Figure 1).