Serum glucose (121 mg/dL, min-max = 59-245 vs. 96 mg/dL, min-max = 71-332; p < 0.001), creatinine (0.9 mg/dL, min-max = 0.42-3.32 vs. 0.75 mg/dL, min-max = 0.27-1.7; p < 0.001), triglyceride (175 mg/dL, min-max = 58-882 vs. 122 mg/dL, min-max = 30-445; p < 0.001), C-reactive protein (CRP) (3.20 ± 1.19 mg/L vs. 2.55 ± 1.42 mg/L; p < 0.001), white blood cell (WBC) count (8.16 ± 2.09 103/mm3 vs. 7.64 ± 1.84 103/mm3; p < 0.001), and TyG index (9.19 ± 0.57 vs. 8.80 ± 0.59; p < 0.001) levels were significantly higher in the peripheral artery disease group than in the control group. Here, CRP is linked to peripheral arterial disease.