Seven parameters were screened, namely, IMDC grade [hazard rate (HR) = 5.26, p < 0.0001], albumin (HR = 0.82, p < 0.0001), calcium (HR = 172.34, p = 0.0005), adverse reaction grade (HR = 0.31, p = 0.0169), Karnofsky score (KPS score, HR = 0.92, p = 0.0442), bone metastasis (HR = 2.85, p = 0.0462), and hemoglobin (HR = 0.97, p = 0.0124) (Table 3). This evidence concerns the gene ALB and bone metastasis.