NOX4 and metastatic malignant neoplasm in the lymph nodes: We found the highest expression of NOX4 in pancreatic body tumors, and in patients with Tumor Size less than 7 cm, with moderate lymph node metastasis, no vascular recidivism or no distant metastasis, high expression of NOX4 was detected in the pancreas (Figures 2A-D, F, I).