Meanwhile, the study found that the 5-year survival rate was 0.51(95% CI 0.37 ~ 0.70) in patients with left colon tumors with high expression of NOX4, the 5-year survival rate for patients with low NOX4 expression was 0.89(95%CI 0.80 ~ 0.99) (28). This evidence concerns the gene NOX4 and colonic neoplasm.