These pathways are commonly dysregulated in HCC and are downstream from many growth factor receptors (e.g. VEGFR, EGFR, fibroblast growth factor receptor (FGFR) and the platelet-derived growth factor receptor (PDGF)) (Dimri and Satyanarayana, 2020). The gene discussed is EGFR; the disease is hepatocellular carcinoma.