ARAP1 and type 2 diabetes mellitus: We have reported that natural antisense lncRNA-ARAP1-AS2 can interact with its sense target gene ARAP1, a type 2 diabetes susceptibility gene product, which finally contributing to the fibrosis process through maintaining the EGFR persistent transactivation in human proximal tubular cells (HK-2) exposed to the high glucose condition (Yang et al., 2019a; Li et al., 2020a; Li et al., 2020b).