DHA reduced the levels of MDA, and nitric oxide in LPS-induced AKI, increased the levels of GSH, CAT, and SOD, restored balance between oxidative and antioxidant and ameliorated LPS-induced renal oxidative stress, which may contribute to the protection of DHA against LPS-induced AKI (Liu et al., 2019). This evidence concerns the gene SOD1 and acute kidney injury.