Literature search on “lncRNA-miRNA pairs” in cancer revealed one lncRNA (MALAT1) -miR125b interaction in laryngocarcinoma (Zong et al., 2021), three lncRNA (TUG1, NEAT1, MALAT1) -miR-34a interactions reported in endometrial cancer, Nasopharyngeal Cancer, Melanoma (Liu et al., 2017; Ji et al., 2019; Li et al., 2019) and three lncRNA (PVT1, NEAT1, and MALAT1) -miR-30a-5p interactions in papillary thyroid carcinoma, gastric cancer, Hepatocellular Carcinoma (Feng et al., 2018; Pan et al., 2018; Rao et al., 2021). The gene discussed is TUG1; the disease is melanoma.