It was reported that ARID1A suppressed histone deacetylase 6 (HDAC6) in OCCC directly, and HDAC6 nuclear expression was associated with immuno- and hypoxia tolerance and cancer stem cell phenotype in OCCC and upregulated following chemotherapy, leading to a poor prognosis (Yano et al., 2018; Yano et al., 2019). The gene discussed is HDAC6; the disease is cancer.