Therefore, according to the results of this study, we speculated that the high expression of ENST00000313807, NON-HSAT194388.1, and COL1A1 in plasma cirexos of patients with SSc, and the low expression of I-miR-29a-3p and has-miR-29b-3p may be indices for the expression of serum albumin and albumin/white in patients with SSc. Here, ALB is linked to systemic sclerosis.