This finding is concordant with a study in India, which was conducted among AIDS patients in Mangalore, Karnataka, and found that patients with CD4 counts of 200 cells/mm3 were at a high risk of developing an advanced form of OIs such as tuberculosis, Pneumocystis jiroveci pneumo-nia, and cryptococcal meningitis (55). This evidence concerns the gene CD4 and Cryptococcal meningitis.