CXCL1 and Sepsis: Although NET production was not directly studied, CXCL1 stimulates ROS-dependent NET formation in COVID-19 (62), deep vein thrombosis (63), and cancer (64), and inhibiting the CXCL1-CXCR2 axis in experimental human and murine sepsis models by reparixin attenuates NET formation, multi-organ injury, and mortality (65).