In the metastatic breast cancer cell line MDA-MB-231, suppression of ROR1 function led to reduced expression of vimentin, SNAIL-1/2, and ZEB1, but increased levels of E-cadherin, CK-19, and ZO-1; in addition, the ability of MDA-MB-231 cells to migrate and invade decreased. This evidence concerns the gene ROR1 and breast cancer.