After adjusting for the covariates (BMI, CD4, AST, TBIL, WBC, Race, whether infected with STDs, initial HAART prescription, marital status, disease stage, WHO clinical stage, infection pathway, and platelet) with p-value of <0.2 (Table 1), the death risk for PLWHA suffering from anemia was significantly increased by 74% (adjusted hazard ratio [AHR]:1.74; 95% confidence interval [CI]:1.03–2.93; p = 0.038) when compared with those without anemia (Table 2). This evidence concerns the gene CD4 and anemia (phenotype).