HINT1 and Gamstorp-Wohlfart syndrome: Loss-of-function changes in the histidine triad nucleotide-binding protein 1 (HINT1) are associated with autosomal recessive axonal neuropathy with neuromyotonia (NMAN [MIM: 137200]) (1), the symptoms of which are similar to those of Charcot-Marie-Tooth (CMT) disease.