Through LASSO regression and Cox regression analysis, we concluded that the characteristics influencing the risk of death in IHD patients based on the training group in this study included age, uric acid, serum total bilirubin, albumin, alkaline phosphatase, and left ventricular ejection fraction, and the nomograms showed moderately good predictive ability by time-dependent ROC curve analysis, C-index, calibration plot, and DCA curve. This evidence concerns the gene ALB and myocardial ischemia.