PTGS2 and gastric ulcer: Theseclasses of medication are commonly used as anti-inflammatory and antipyreticmedications.4 IBP acts by inhabiting hormonesthat cause pain in the body cyclooxygenase-2 (COX-2), the dominantnonprescription pharmaceutical used worldwide.5 Some effects of ibuprofen are gastric ulceration, bleeding, kidneyproblems, bowel inflammation, mucosal damage, vomiting, and cardiovascularissues.6 DCF works by reducing substancesthat cause pain and inflammation and treating mild to moderate pain.