Univariate analysis showed that TUBB2B was significantly related to OS in both TCGA (hazard ratio [HR] = 1.06, 95% confidence interval [CI]: 1.02–1.10, and p = 0.004) and GSE14520 HCC patients (HR = 1.36, 95% CI: 1.10–1.69, and p = 0.005) (Supplementary Tables 6 and 7). The gene discussed is TUBB2B; the disease is hepatocellular carcinoma.