In recent years, studies have reported that CCL2 is closely related to chronic non‐controllable inflammation, such as cirrhosis, neuropathic pain, insulin resistance, atherosclerosis, deforming arthritis, ischemic injury, cancer, and so on.17, 18, 19, 20, 21, 22, 23, 24, 25. Here, CCL2 is linked to Insulin resistance.