In recent years, studies have reported that CCL2 is closely related to chronic non‐controllable inflammation, such as cirrhosis, neuropathic pain, insulin resistance, atherosclerosis, deforming arthritis, ischemic injury, cancer, and so on.17, 18, 19, 20, 21, 22, 23, 24, 25. The gene discussed is CCL2; the disease is atherosclerosis.