DKC1 and chronic myelogenous leukemia, BCR-ABL1 positive: Next, we checked the transcriptional activity of the DKC1 gene—nucleolar protein, which is responsible for maintaining TERC stability by interacting with H/ACA consensus sequence in TERC. The conducted comparison between the expression of the DKC1 gene in two groups of CML CD34+ showed a statistically significant increase (2.1-fold) of DKC1 expression in CML-BP cells in comparison with CML-CP cells (Fig. 2c).