Consistent with our previous findings that NUDT22 expression is induced by cMYC and regulated by p53, overall survival of patients with high NUDT22 and cMYC expression has a significantly worse outcome in several types of cancer (Supplementary Fig. 7A, B) and MYC and NUDT22 expression correlates in the CCLE dataset of 1070 cancer cell lines (Supplementary Fig. 7C). This evidence concerns the gene TP53 and cancer.