NUDT22 and cancer: Consistent with our previous findings that NUDT22 expression is induced by cMYC and regulated by p53, overall survival of patients with high NUDT22 and cMYC expression has a significantly worse outcome in several types of cancer (Supplementary Fig. 7A, B) and MYC and NUDT22 expression correlates in the CCLE dataset of 1070 cancer cell lines (Supplementary Fig. 7C).