CD4 and neoplasm: Tumor immune-microenvironment analysis showed that the number of naïve B cells, plasma cells, and CD8 T cells was significantly higher in the low-risk group than in the high-risk group, whereas that of resting memory CD4 T cells, M0 macrophages, and activated dendritic cells were significantly higher in the high-risk group (P < 0.05, Fig. 7B).