Moreover, missense mutations were detected in CD44 and CD19 (associated with acute myeloid leukemogenesis), LTK (associated with poorly differentiated adenocarcinoma), NOTCH2 (associated with diffuse large B-cell tumorigenesis), and CNTN2 (associated with T-cell lymphoma; Table 3). The gene discussed is NOTCH2; the disease is T-cell non-Hodgkin lymphoma.