A clinical trial conducted by Jelena et al. on 189 patients with T2DM and/or arterial HT reported a positive correlation between Gal-3 levels and T2DM and HT, as well as a positive correlation with left ventricular weight, suggesting a potential role of Gal-3 for the early detection of structural and functional changes in the myocardium [106]. This evidence concerns the gene LGALS3 and hematocrit.