In addition, TRIM56 expression was significantly different among glioma subtypes (IDH-wild type vs. IDH-mutant, MGMT promoter methylated vs. MGMT promoter unmethylated, and Chromosome 1p19q codeletion vs. Chromosome 1p19q non-codeletion) in the CGGA_mRNAseq_325 and TCGA databases (Fig. 1B–D and Supplementary Fig. 3C–E). Here, MGMT is linked to central nervous system cancer.