To test whether YTHDF2 overexpression influenced cisplatin resistance, HGC27 and MGC803 cells with YTHDF2 stable overexpression (LV-YTHDF2) were cultured with cisplatin followed by colony formation assays and we found that YTHDF2 overexpression increased the cisplatin sensitivity of GC cells (Fig. 7A). This evidence concerns the gene YTHDF2 and gastric cancer.