Subsequent experiments verified the effect of ginseng fat-soluble components on the expression of EGFR, KDR, MAPK3, PTPN11 and CTNNB1, which preliminarily indicated that ginseng fat-soluble components may affect the regulation of related pathways by down-regulating these five key proteins and thus may have an impact on the treatment of lung cancer. This evidence concerns the gene PTPN11 and lung cancer.