Distant metastasis-free survival (DMFS) and overall survival (OS) of patients with breast cancer who develop ILRR are associated with age at diagnosis, type of surgery performed for primary breast cancer, tumor size, nodal metastasis, hormone receptor status of the primary tumor, disease-free interval (DFI), and ILRR site [7–11]. This evidence concerns the gene NR4A1 and breast carcinoma.