INS and type 2 diabetes mellitus: Within the group of miRNAs differentially expressed in T2D islets and involved in the regulation of insulin secretion, we found increased expression of miR-187-3p, miR-124-3p, miR-463-3p, miR-130a-3p, miR-130b-3p, miR-152-3p, and miR-200c-3p (34‐38) to be involved in β-cell dysfunction, while decreased expression of miR-7-5p (miR-7a; (39)) seems to be a mechanism by which this miRNA exerts a compensatory regulatory effect on exocytosis (Fig. 2).