APC2 and hypertensive disorder: For DBP, these common genes took part in Wnt signaling pathway (WNT3A, APC2, and GNA14), ubiquitin proteasome pathway (SAE1), and RNA degradation pathway (CNOT10), etc. Moreover, we also found many common enrichment terms, such as voltage-gated calcium channel activity [66], NADH dehydrogenase (ubiquinone) activity [67], PPAR signaling pathway [68], and acetylcholine receptor activity [69], for which the relationships with hypertension were clear.